Human Pathophysiology.
HCR 240 Module 1 Learning Guide
pg. 1 of 4
MODULE REFLECTION – In the box below, reflect on the course material and activities for this module. If you did not complete all the activities, did you have any questions or comments relating to this? What content did you find the most interesting and why? This should be a 4-5 sentence paragraph.
MODULE CONTENT REVIEW STUDY GUIDE CHAPTER 2 – CELLULAR INJURY, ADAPTATIONS, AND MALADAPTIVE CHANGES Define the following terms:
Term Definition
Etiology
Histology
Biopsy
Pathognomic Changes
Atrophy
Hypertrophy
Hyperplasia
Metaplasia
Dysplasia
Neoplasia
Hypoxia
Apoptosis
Necrosis
Infarction
Gangrene
HCR 240 Module 1 Learning Guide
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CHAPTER 3 – GENETIC BASIS OF DISEASE Genetic Diseases to Know – Fill in the table below with information from textbook or videos regarding type of genetic or chromosomal disorder occurs, signs and symptoms, diagnostic testing, and possible treatments:
Genetic Disease or Syndrome
Type of Genetic / Chromosomal Disorder
Signs and Symptoms of Disease
Diagnostic Testing Possible Treatments
Cystic Fibrosis
Tay Sachs Disease
Down Syndrome
Huntington’s Disease
CHAPTER 9 – INFLAMMATION AND DYSFUNCTIONAL WOUND HEALING Define and give examples of the terms below using your textbook and/or videos:
Term Definition Examples
Acute inflammation
Purulent exudate
Abscess
Transudate
Effusion
Leukocytosis
Chemotaxis
HCR 240 Module 1 Learning Guide
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Term Definition Examples
Cytokines
Fibrinogen
White Blood Cells
Pyrogens
Lymphadenopathy
Histamine
Chronic inflammation
Four phases of wound healing
Hemostasis
Wound retraction
Primary intention
Secondary intention
Tertiary intention
Eschar
Debridement
Wound dehiscence
Wound evisceration
Keloid
Contractures
Stricture
Fistula
Adhesion
HCR 240 Module 1 Learning Guide
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CHAPTER 10 – INFECTIOUS DISEASES These are the required infectious diseases you should know. Fill in the table to answer type, signs, and symptoms of each:
Pathogen Type (Bacteria, Virus, Fungus, or Parasite)
Signs and Symptoms One Interesting Fact / Statistic of Disease
Staphylococcal Infections
Streptococcal Infections
Pneumonia Infections
Bacterial Meningitis: Haemophiles influenzae
GI Tract Infections – Escherichia coli
Common Cold
Influenza
Epstein Barr
MMR – Measles, Mumps, Rubella
Varicella
Herpes Simplex
Candida
Malaria
- Chapter 2 – Cellular Injury, Adaptations, and Maladaptive Changes
- DefinitionEtiology: original cause of cell alteration/disease
- DefinitionHistology: microscopic study of cells/tissues
- DefinitionBiopsy: sample of histological analysis
- DefinitionPathognomic Changes: histological findings that represent disease
- DefinitionAtrophy: cells shrink in size due to reduction of metabolic demand
- DefinitionHypertrophy: increase in cell size
- DefinitionHyperplasia: increase number of cells to organ/tissue
- DefinitionMetaplasia: replace one cell type with another
- DefinitionDysplasia: derranged cellular growth, result of chronic inflammation, or precancerous condition
- DefinitionNeoplasia: “new growth” known to be disorganized, uncoordinated, cancerous.
- DefinitionHypoxia: diminished O2 to cells, due to ischemia, problem’s with RBC’s, and pulmonary issues
- DefinitionApoptosis: programmed cell death. does not cause inflammation
- DefinitionNecrosis: cell death due to injury-initiates inflammatory reaction
- DefinitionInfarction: ischemic necrosis
- DefinitionGangrene: prolonged ischemia, infarction, and necrosis
- Type of Genetic Chromosomal DisorderCystic Fibrosis:
- Signs and Symptoms of DiseaseCystic Fibrosis:
- Diagnostic TestingCystic Fibrosis:
- Possible TreatmentsCystic Fibrosis:
- Type of Genetic Chromosomal DisorderTay Sachs Disease:
- Signs and Symptoms of DiseaseTay Sachs Disease:
- Diagnostic TestingTay Sachs Disease:
- Possible TreatmentsTay Sachs Disease:
- Type of Genetic Chromosomal DisorderDown Syndrome:
- Signs and Symptoms of DiseaseDown Syndrome:
- Diagnostic TestingDown Syndrome:
- Possible TreatmentsDown Syndrome:
- Type of Genetic Chromosomal DisorderHuntingtons Disease:
- Signs and Symptoms of DiseaseHuntingtons Disease:
- Diagnostic TestingHuntingtons Disease:
- Possible TreatmentsHuntingtons Disease:
- DefinitionAcute inflammation:
- ExamplesAcute inflammation:
- DefinitionPurulent exudate:
- ExamplesPurulent exudate:
- DefinitionAbscess:
- ExamplesAbscess:
- DefinitionTransudate:
- ExamplesTransudate:
- DefinitionEffusion:
- ExamplesEffusion:
- DefinitionLeukocytosis:
- ExamplesLeukocytosis:
- DefinitionChemotaxis:
- ExamplesChemotaxis:
- DefinitionCytokines:
- ExamplesCytokines:
- DefinitionFibrinogen:
- ExamplesFibrinogen:
- DefinitionWhite Blood Cells:
- ExamplesWhite Blood Cells:
- DefinitionPyrogens:
- ExamplesPyrogens:
- DefinitionLymphadenopathy:
- ExamplesLymphadenopathy:
- DefinitionHistamine:
- ExamplesHistamine:
- DefinitionChronic inflammation:
- ExamplesChronic inflammation:
- DefinitionFour phases of wound healing:
- ExamplesFour phases of wound healing:
- DefinitionHemostasis:
- ExamplesHemostasis:
- DefinitionWound retraction:
- ExamplesWound retraction:
- DefinitionPrimary intention:
- ExamplesPrimary intention:
- DefinitionSecondary intention:
- ExamplesSecondary intention:
- DefinitionTertiary intention:
- ExamplesTertiary intention:
- DefinitionEschar:
- ExamplesEschar:
- DefinitionDebridement:
- ExamplesDebridement:
- DefinitionWound dehiscence:
- ExamplesWound dehiscence:
- DefinitionWound evisceration:
- ExamplesWound evisceration:
- DefinitionKeloid:
- ExamplesKeloid:
- DefinitionContractures:
- ExamplesContractures:
- DefinitionStricture:
- ExamplesStricture:
- DefinitionFistula:
- ExamplesFistula:
- DefinitionAdhesion:
- ExamplesAdhesion:
- Type Bacteria Virus Fungus or ParasiteStaphylococcal Infections:
- Signs and SymptomsStaphylococcal Infections:
- One Interesting Fact Statistic of DiseaseStaphylococcal Infections:
- Type Bacteria Virus Fungus or ParasiteStreptococcal Infections:
- Signs and SymptomsStreptococcal Infections:
- One Interesting Fact Statistic of DiseaseStreptococcal Infections:
- Type Bacteria Virus Fungus or ParasitePneumonia Infections:
- Signs and SymptomsPneumonia Infections:
- One Interesting Fact Statistic of DiseasePneumonia Infections:
- Type Bacteria Virus Fungus or ParasiteBacterial Meningitis Haemophiles influenzae:
- Signs and SymptomsBacterial Meningitis Haemophiles influenzae:
- One Interesting Fact Statistic of DiseaseBacterial Meningitis Haemophiles influenzae:
- Type Bacteria Virus Fungus or ParasiteGI Tract Infections Escherichia coli:
- Signs and SymptomsGI Tract Infections Escherichia coli:
- One Interesting Fact Statistic of DiseaseGI Tract Infections Escherichia coli:
- Type Bacteria Virus Fungus or ParasiteCommon Cold:
- Signs and SymptomsCommon Cold:
- One Interesting Fact Statistic of DiseaseCommon Cold:
- Type Bacteria Virus Fungus or ParasiteInfluenza:
- Signs and SymptomsInfluenza:
- One Interesting Fact Statistic of DiseaseInfluenza:
- Type Bacteria Virus Fungus or ParasiteEpstein Barr:
- Signs and SymptomsEpstein Barr:
- One Interesting Fact Statistic of DiseaseEpstein Barr:
- Type Bacteria Virus Fungus or ParasiteMMR Measles Mumps Rubella:
- Signs and SymptomsMMR Measles Mumps Rubella:
- One Interesting Fact Statistic of DiseaseMMR Measles Mumps Rubella:
- Type Bacteria Virus Fungus or ParasiteVaricella:
- Signs and SymptomsVaricella:
- One Interesting Fact Statistic of DiseaseVaricella:
- Type Bacteria Virus Fungus or ParasiteHerpes Simplex:
- Signs and SymptomsHerpes Simplex:
- One Interesting Fact Statistic of DiseaseHerpes Simplex:
- Type Bacteria Virus Fungus or ParasiteCandida:
- Signs and SymptomsCandida:
- One Interesting Fact Statistic of DiseaseCandida:
- Type Bacteria Virus Fungus or ParasiteMalaria:
- Signs and SymptomsMalaria:
- One Interesting Fact Statistic of DiseaseMalaria:
- ModuleReflection:
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