1.  True or false: In a DNA molecule, the bases are covalently bonded to each other.

2. True or false: During DNA replication, the strands of parent DNA are unwound.

3. True or false: The function of messenger RNA (mRNA) is to transfer amino acids to the ribosomes during protein synthesis.

4. True or false: The Genetic Code varies from species to species.

5. True or false: The completion of the Human Genome Project allowed us to sequence all of the human genome and to know the function of all of the genes.

6. In __________ every three bases is a/an _____________ that codes for a/an _____________.

7. True or false: During translation, the anticodon of tRNA pairs with bases in mRNA.

8. The removal of a nucleotide from a gene in the DNA leads to a _______________.

9.  True or false: Cloning is a natural process for some organisms.

10. True or false: Lactose metabolizing enzymes are produced when RNA polymerase binds to the operator on the lac operon in the absence of lactose.

11. If one strand of DNA has the following sequence: CGGCTAATCGCC, what would the sequence of the complimentary strand be?

12. If the codon of an mRNA strand is UGC, the anticodon of the tRNA would be ___________ and the amino acid, ____________, will be added to the growing peptide chain.

13. True or false: In a normal cell, Ras is a continuously active protein that functions in signaling pathways, several of which promote the cell cycle.

14. True or false: Chorionic villi sampling (CVS) is a much safer procedure than amniocentesis because CVS is done later in pregnancy.

15. True or false: Transcriptional control is the most important level of gene control.

16. X-linked recessive disorders often pass from grandfather to granddaughter.

17. True or false: After it is synthesized, mRNA may linger in the nucleus before moving into the cytoplasm.

18. True or false: Two parents are affected with a genetic disorder. They produce an unaffected child. The disorder is likely transmitted as an autosomal dominant trait.

19. True or false: An enhancer region of DNA is adjacent to the promoter.

20. True or false: The only two methods by which fetal cells can be obtained for testing are amniocentesis and chorionic villi sampling.

21. What purpose does a cell-signaling pathway serve in a multicellular organism?

22. True or false: Some genetic mutations can be determined by testing for proteins.

23. True or false: A regulatory gene codes for a protein that activates the genes in an operon.

24. True or false: Cancer cells show a high degree of contact inhibition.

25. The major way in which therapeutic cloning and reproductive cloning differ is what?

26. True or false: Proto-oncogenes may code for growth factors.

27. True or false: Telomerase is highly active in cancer cells.

28. True or false: Angiogensis is not a suspected cause of cancer.

29. True or false: A karyotype can be done using any cell in the body.

30. True or false: An exchange of chromosomal segments between two nonhomologous chromosomes is a/an translocation.

31.  In a duplication, a person has more than two alleles for a certain trait.

32. In an autosomal dominant genetic disorder, if both parents have the disorder, what is the chance that their sons will have the disorder?

33. A male has a particular X-linked recessive genetic disorder. His partner is normal, but her father had the disorder. What is the chance that their sons will have the disorder?

34. Phenylketonuria (PKU) is an autosomal Phenylketonuria (PKU) is an autosomal recessive disorder. If a woman who does not have PKU gives birth to a child who has PKU, which of the following men, based on this information alone, could not be the father of the child?

35. True or false: An abnormality in DNA sequence used in a test to determine an abnormal allele is called a genetic marker.

36. True or false: A genetic profile can detect mutations in a person’s genes.

37. The insertion of genetic material into human cells for treatment of a disorder is called what?

39. What is the difference between ex vivo gene therapy and in vivo gene therapy?

40. True or false: Ultrasound images determine the karyotype of the fetus.

41. An autosomal recessive disorder that occurs among all ethnic groups, in which chloride ions fail to pass through a plasma membrane channel protein in the cells and leads these patients to develop thick mucus in their bronchial tubes and pancreatic ducts is ________.

42. What disorders are present only in males and are passed from father to all sons but not to daughters.

43. True or false: mRNA processing occurs after transcription.

44. A testable explanation of a broad range of related phenomena that is relied upon by scientists with a high degree of confidence is referred to as ________.

45. The smaller unit molecules (monomers) which combine to form proteins and polypeptides are called ____________.

46. Enzymes, some hormones, and structural molecules like keratin and collagen are examples of ______________.

47. An atom that has gained or lost electrons is referred to as _______________.

48. Cell membranes consist of _____________.

49.  Which transport mechanism requires ATP to move materials across a plasma membrane?

50. A cell is placed in a solution.  If the cell is observed to shrink, the solution must be _________________ relative to the interior of the cell.

51.  What are the 1st and 2nd energy laws?

52. In higher cells, cellular (aerobic) respiration with production of adenosine triphosphate (ATP) is carried out in the _______________.

53. Meiosis differs from mitosis because _______________.

54. Leaves are green because ____________.

55. Many human traits such as eye color and height are controlled by _______________.

56. ______________ is a nucleic acid base found in ribonucleic acid (RNA) but not in deoxyribonucleic acid (DNA).

57. The polymerase chain reaction (PCR) is a method of ________________.

58. The normal complement of sex chromosomes for a human male is ___________.

59. An allele is ____________.

60. A visual display of metaphase chromosomes arranged by size, shape, and banding pattern is ______.

61. The part of an enzyme that “fits” its substrate is called its __________ site.

62. True or false: recombinant deoxyribonucleic acid (rDNA) technology estimates the age of a rock sample.

 

63. True or false: A mutation of a tumor suppressor gene is most likely to cause a cell to become cancerous.

 

"Looking for a Similar Assignment? Get Expert Help at an Amazing Discount!"

 

Opioid Crisis in Winston-Salem, NC

Professor Feedback:

 

Mara: There is no clear identification of option 2 in the title. Your outline gives a good idea of what you will need to cover in the final project and is detailed enough (more than the assigned 2 pages). It shows the logic of your analysis of opioid abuse in Winston-Salem. You cited several appropriate sources. It is clearly organized in Symptoms, Diagnosis, Cure, and Prevention sections, and is written correctly as an outline. APA is ok.

 

I. Introduction

A. Opioid crisis entails extensive opioid overuse from medical and non-medical prescriptions

B. This issue started in the late 1990s, following the increased prescription of opioids for the management of pain. It led to an increase in the usage of opioids, both prescription and non-prescription, throughout the U.S in subsequent years (Guy Jr, Zhang, Bohm, Losby, Lewis, Young & Dowell, 2017).

C. Winston-Salem, North Carolina, is not excluded from this opioid crisis.

a. Winston-Salem is a city in Forsyth County. According to Briker (2008), the town emerged following the merger of Winston and Salem towns in 1913.

D. Thesis: Opioid crisis is a significant public health issue in Winston-Salem, calling for action.

II. Body paragraphs

A. Symptoms

a. The issue affects mostly non-Hispanic whites aged 18 and above.

i. People aged 26 years and older are the most frequent users of prescription opioids, while the age group with the highest non-medical opioids use is young adults between the ages of 18 and 25 (Green, 2017).

b. The signs of symptoms of this crisis among individuals include dependence on opioids, prioritization of acquisition and use of opioids over other activities such as school and work, and weight loss. Other symptoms include lack of hygiene, drowsiness, isolation from family and friends, engaging in risky behaviors, being nervous, losing interest in activities previously enjoyed, and experiencing financial hardships (Green, 2017).

c. In the community, the symptoms indicate that opioid use has become a crisis include increased health care and criminal justice costs (Birnbaum, White, Schiller, Waldman, Cleveland & Roland, 2011).

B. Diagnosis

a. One of the primary roots of the opioid crisis is the initiation of opioids for pain management (Green, 2017).

i. Increased number of people affected by chronic pain pushed the use of painkilling opioids.

b. Continued use of opioids beyond doctor prescriptions to minimize pain or induce eutrophic feelings (Green, 2017).

c. Opioids are inexpensive to acquire.

i. When compared to alternative intervention for pain management such as physical therapy, opioids are relatively inexpensive (Green, 2017).

d. Other communities affected by this opioid crisis include Lockbourne in Pickaway County, Ohio, and Kermit in Mingo County in West Virginia.

e. Measures to address this issue by these communities:

i. Providing education and distributing naloxone (Palombi, Olivarez, Bennett & Hawthorne, 2019)

ii. Educating members of the community on safe usage, storing, and discarding of prescription medication

iii. Providing support for community members in the recovery process (Palombi et al., 2019)

C. Cure

a. Pharmacological treatment

i. Medications too address the issue includes opioid agonists such as methadone, acetate, and levomethadyl, opioid antagonists such as naloxone and naltrexone, and non-opioid medication including clonidine and lofexidine (Veilleux, Colvin, Anderson, York & Heinz, 2010).

b. Psychosocial treatment

i. Biofeedback, cognitive behavioral therapy, and psychodynamic therapies improve relapses and treatment retention (Veilleux et al., 2010).

c. Precision Addiction Management has been suggested as an approach to the effectively compact opioid crisis (Blum, Gondré-Lewis, Baron, Thanos, Braverman, Neary, … & Badgaiyan, 2018).

d. Increasing access to treatment and recovery sustenance would enable people with this problem to seek treatment.

D. Prevention

a. Prescription monitoring programs (Hahn, 2011)

b. Ending supply of unfitting prescriptions and illegal opioids

c. Enhancing maternal and prenatal care for females struggling with substance misuse (Hahn, 2011)

d. Supporting the youths through targeted initiatives to lessen youth misuses of opioids

e. Enhance awareness on the risks of opioids use and the costs of opioid misuse on individuals and the community (Hahn, 2011).

III. Conclusion

A. The opioid crisis is a huge public health issue, and thus, addressing this problem is a priority for communities.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

References

Birnbaum, H. G., White, A. G., Schiller, M., Waldman, T., Cleveland, J. M., & Roland, C. L. (2011). Societal costs of prescription opioid abuse, dependence, and misuse in the United States. Pain medicine, 12(4), 657-667. https://www.asam.org/docs/advocacy/societal-costs-of-prescription-opioid-abuse-dependence-and-misuse-in-the-united-states.pdf

Blum, K., Gondré-Lewis, M. C., Baron, D., Thanos, P. K., Braverman, E. R., Neary, J., … & Badgaiyan, R. D. (2018). Introducing precision addiction management of reward deficiency syndrome, the construct that underpins all addictive behaviors. Frontiers in psychiatry, 9, 548. https://www.frontiersin.org/articles/10.3389/fpsyt.2018.00548/full

Bricker, M. L. (2008). Winston-Salem: A twin city history. The History Press.

Green, J. (2017). Epidemiology of opioid abuse and addiction. Journal of Emergency Nursing, 43(2), 106-113.

Guy Jr, G. P., Zhang, K., Bohm, M. K., Losby, J., Lewis, B., Young, R., … & Dowell, D. (2017). Vital signs: changes in opioid prescribing in the United States, 2006–2015. MMWR. Morbidity and mortality weekly report, 66(26), 697-704 https://www.cdc.gov/mmwr/volumes/66/wr/mm6626a4.htm

Hahn, K. L. (2011). Strategies to prevent opioid misuse, abuse, and diversion that may also reduce the associated costs. American health & drug benefits, 4(2), 107-114 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4106581/pdf/ahdb-04-107.pdf

Palombi, L., Olivarez, M., Bennett, L., & Hawthorne, A. N. (2019). Community Forums to Address the Opioid Crisis: An Effective Grassroots Approach to Rural Community Engagement. Substance abuse: research and treatment, 13, 1178221819827595. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378421/pdf/10.1177_1178221819827595.pdf

Veilleux, J. C., Colvin, P. J., Anderson, J., York, C., & Heinz, A. J. (2010). A review of opioid dependence treatment: pharmacological and psychosocial interventions to treat opioid addiction. Clinical psychology review, 30(2), 155-166.

 

"Looking for a Similar Assignment? Get Expert Help at an Amazing Discount!"